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emergency medicine

Practice targeted AMC-style multiple-choice questions on emergency medicine.

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Acute cholecystitis with gallbladder wall thickening, a large gallstone, and a large gallbladder
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 55-year-old female presents to the emergency department with a 24-hour history of severe right upper quadrant pain radiating to her back, associated with nausea, vomiting, and subjective fever. On examination, she is febrile (38.5°C) and has marked tenderness and guarding in the right upper quadrant. Her vital signs are otherwise stable. Blood tests reveal a white cell count of 15 x 10^9/L and C-reactive protein of 120 mg/L. Liver function tests, including bilirubin, are within normal limits. She is initiated on intravenous fluids and broad-spectrum antibiotics. Imaging is subsequently performed. Considering the patient's clinical presentation and the findings demonstrated in the provided imaging, what is the most appropriate definitive management strategy?

A. Endoscopic retrograde cholangiopancreatography (ERCP)
B. Delayed laparoscopic cholecystectomy in 6-8 weeks
C. Percutaneous cholecystostomy tube insertion
D. Early laparoscopic cholecystectomy within 72 hours
E. Continue conservative management with IV antibiotics and analgesia only
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CT scan showing hemothorax caused by warfarin use
Image by Cevik Y CC BY 3.0 · Source

A 72-year-old male presents to the emergency department complaining of sudden onset shortness of breath and right-sided chest pain. He reports that the pain started acutely this morning and has been gradually worsening. He has a history of atrial fibrillation and has been taking warfarin for the past 5 years. He denies any recent trauma or injury. On examination, his vital signs are: heart rate 110 bpm, blood pressure 100/60 mmHg, respiratory rate 28 breaths per minute, oxygen saturation 88% on room air. Auscultation reveals decreased breath sounds on the right side. The patient is pale and diaphoretic. A chest X-ray was initially performed, followed by the image shown. Given the clinical presentation and the findings on the image, what is the MOST appropriate next step in management?

A. Administer protamine sulfate
B. Perform a thoracentesis
C. Administer intravenous antibiotics
D. Order a ventilation/perfusion scan
E. Insert a chest tube
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A 45-year-old woman presents to the emergency department with a 3-day history of progressive shortness of breath, dry cough, and fatigue. She has a history of systemic lupus erythematosus (SLE) and is currently on hydroxychloroquine and low-dose prednisone. She denies fever, chest pain, or recent travel. On examination, her temperature is 37.2°C, blood pressure is 110/70 mmHg, heart rate is 95 bpm, respiratory rate is 22 breaths per minute, and oxygen saturation is 89% on room air. Lung auscultation reveals bilateral basal crackles. Laboratory tests show a hemoglobin level of 10.5 g/dL, white blood cell count of 4,000/mm³, and platelets of 150,000/mm³. Arterial blood gas analysis reveals a pH of 7.45, PaCO2 of 35 mmHg, and PaO2 of 55 mmHg. A chest X-ray shows bilateral interstitial infiltrates. Which of the following is the most appropriate next step in management?

A. Initiation of non-invasive ventilation
B. High-dose intravenous methylprednisolone
C. Intravenous cyclophosphamide
D. Empirical broad-spectrum antibiotics
E. Bronchoscopy with bronchoalveolar lavage
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A 68-year-old man presents to the emergency department with 90 minutes of crushing chest pain radiating to his left arm. He is diaphoretic and anxious. ECG shows 3mm ST elevation in leads V2-V4. His blood pressure is 130/80 mmHg, heart rate 75 bpm. What is the most appropriate immediate next step in management?

A. Arrange urgent coronary CT angiography
B. Administer dual antiplatelet therapy and heparin
C. Prepare for intravenous fibrinolysis
D. Activate the cardiac catheterisation laboratory for primary PCI
E. Obtain serial cardiac biomarkers
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 55-year-old male presents to the emergency department with a 2-day history of left lower quadrant abdominal pain, associated with a low-grade fever (38.1°C) and mild nausea. He denies vomiting, diarrhoea, or rectal bleeding. On examination, he has localised tenderness in the left iliac fossa. His vital signs are stable: BP 130/80 mmHg, HR 78 bpm, RR 16/min, SpO2 98% on air. Blood tests show a white cell count of 12.5 x 10^9/L and CRP 45 mg/L. An abdominal CT scan is performed (image provided). Following successful management of this acute episode, what is the most appropriate next step regarding long-term assessment of the colon?

A. Repeat CT scan in 3 months to assess resolution.
B. Refer for surgical consultation for elective colectomy.
C. Schedule a colonoscopy within 6-8 weeks.
D. Perform a barium enema to assess the extent of diverticular disease.
E. Advise a high-fibre diet and no further investigation unless symptoms recur.
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A 32-year-old woman presents to the emergency department with a 2-day history of fever, malaise, and a painful, swollen left knee. She denies any recent trauma or travel history. She has no significant past medical history and is not on any medications. On examination, her temperature is 38.7°C, heart rate is 110 bpm, and blood pressure is 120/80 mmHg. The left knee is erythematous, warm, and tender with a moderate effusion, and she has limited range of motion due to pain. Laboratory tests reveal leukocytosis with a left shift. Blood cultures are pending. What is the most appropriate next step in the management of this patient?

A. Start empirical intravenous antibiotics
B. Arthrocentesis of the left knee
C. Administer oral NSAIDs
D. Refer to rheumatology for further evaluation
E. Order an MRI of the knee
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A 45-year-old man presents to the emergency department with sudden onset of severe abdominal pain radiating to the back. He is a smoker and has a history of hypertension. On examination, he is diaphoretic, with a heart rate of 120 bpm and blood pressure of 90/60 mmHg. Abdominal examination reveals a pulsatile mass in the midline. What is the most likely diagnosis?

A. Acute pancreatitis
B. Ruptured abdominal aortic aneurysm
C. Acute mesenteric ischemia
D. Perforated peptic ulcer
E. Renal colic
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Ultrasonographic picture taken from a patient with left ureteral stone with hydronephrosis, created in Taiwan
Image by morning2k CC BY 2.5 · Source

A 45-year-old male presents to the ED with left flank pain radiating to his groin. He reports nausea but denies fever or dysuria. Vitals are stable. A point-of-care ultrasound is performed, with the image shown. Assuming no contraindications, what is the MOST appropriate next step in management?

A. Prescribe oral tamsulosin and discharge home
B. Insert an indwelling urinary catheter
C. Consult urology for emergent stent placement
D. Order a non-contrast CT scan of the abdomen and pelvis
E. Administer intravenous ketorolac
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Synchronous multiple small bowel intussusceptions in an adult with blue rubber bleb naevus syndrome. CT scan of abdomen showing i) multiple intussusceptions demonstrating doughnut signs (white arrows), intussusceptiens [A], intussusceptum [B], distended loop of small

bowel [C] and ii) haemangioma of right quadratus lumborum muscle (dark arrow).
Image by Lee C, Debnath D, Whitburn T, Farrugia M, Gonzalez F CC BY 2.0 · Source

A 45-year-old male with a known history of Blue Rubber Bleb Naevus Syndrome, characterised by recurrent gastrointestinal bleeding and multiple cutaneous vascular lesions, presents to the emergency department with acute onset severe, colicky abdominal pain, nausea, and vomiting. On examination, his abdomen is distended and diffusely tender with reduced bowel sounds. Vital signs are within normal limits. An urgent abdominal CT scan is performed. Based on the clinical presentation and the findings demonstrated in the image, what is the most appropriate immediate next step in management?

A. Urgent surgical exploration and reduction/resection
B. Attempt air enema reduction under fluoroscopy
C. Urgent upper gastrointestinal endoscopy for reduction
D. Nasogastric tube insertion, intravenous fluids, and observation
E. Obtain an urgent abdominal MRI for further characterisation
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An incarcerated inguinal hernia as seen on CT
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 78-year-old male presents to the emergency department with a 6-hour history of sudden onset, severe pain and swelling in his right groin. He reports nausea but no vomiting. On examination, there is a tender, firm, non-reducible lump in the right inguinal region. Bowel sounds are present. Vitals are stable: BP 130/80, HR 75, Temp 36.8°C. A CT scan of the pelvis is performed, shown in the image. Considering the patient's acute presentation, physical examination findings, and the specific anatomical relationship demonstrated in the image, what is the most critical potential complication requiring urgent surgical assessment?

A. Epididymo-orchitis
B. Deep vein thrombosis
C. Bowel strangulation
D. Peritonitis
E. Bowel obstruction
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Acute cholecystitis with gallbladder wall thickening, a large gallstone, and a large gallbladder
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 65-year-old male presents to the emergency department with 2 days of constant right upper quadrant pain radiating to the back, associated with nausea and subjective fever. On examination, he is febrile (38.5°C) with significant tenderness and a positive Murphy's sign in the right upper quadrant. His white cell count is elevated at 15 x 10^9/L, and CRP is 120 mg/L. Liver function tests are within normal limits. Considering the clinical findings and the provided imaging, what is the most appropriate next step in the management of this patient?

A. Laparoscopic cholecystectomy within 24-72 hours
B. Urgent endoscopic retrograde cholangiopancreatography (ERCP)
C. Percutaneous cholecystostomy insertion
D. Repeat abdominal CT scan in 24 hours
E. Continue medical management with intravenous antibiotics and analgesia only
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A 68-year-old man with a history of poorly controlled type 2 diabetes, hypertension, and chronic kidney disease (stage 3) presents to the emergency department with severe abdominal pain and vomiting. On examination, he has a distended abdomen with diffuse tenderness and guarding. His vital signs show a blood pressure of 90/60 mmHg, heart rate of 110 bpm, and a temperature of 38.5°C. Laboratory tests reveal leukocytosis, elevated serum lactate, and worsening renal function. A CT scan of the abdomen shows pneumoperitoneum and free fluid, suggesting perforated viscus. What is the most appropriate next step in the management of this patient?

A. Immediate exploratory laparotomy
B. Administer intravenous fluids and reassess in 2 hours
C. Initiate broad-spectrum antibiotics and observe
D. Consult nephrology for dialysis before surgery
E. Perform a diagnostic laparoscopy
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A 32-year-old woman presents to the emergency department with severe right lower abdominal pain, nausea, and vomiting. She reports that the pain started suddenly a few hours ago and has been worsening. Her last menstrual period was two weeks ago. On examination, she has tenderness and guarding in the right lower quadrant. A pregnancy test is negative. What is the most likely diagnosis?

A. Pelvic inflammatory disease
B. Renal colic
C. Ovarian torsion
D. Ectopic pregnancy
E. Acute appendicitis
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 55-year-old male presents to the emergency department with a 2-day history of left lower quadrant abdominal pain, associated with a low-grade fever (38.1°C) and mild nausea. He denies vomiting, diarrhoea, or rectal bleeding. On examination, he has localised tenderness in the left iliac fossa. His vital signs are stable: BP 130/80 mmHg, HR 78 bpm, RR 16/min, SpO2 98% on air. Blood tests show a white cell count of 12.5 x 10^9/L and CRP 45 mg/L. An abdominal CT scan is performed (image provided). Based on the clinical presentation and the provided image, what is the most appropriate setting for this patient's initial management?

A. Inpatient admission for intravenous antibiotics and observation.
B. Outpatient management with oral antibiotics and analgesia.
C. Admission for bowel rest and total parenteral nutrition.
D. Urgent surgical consultation for potential intervention.
E. Discharge home with only analgesia and dietary advice.
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Synchronous multiple small bowel intussusceptions in an adult with blue rubber bleb naevus syndrome. CT scan of abdomen showing i) multiple intussusceptions demonstrating doughnut signs (white arrows), intussusceptiens [A], intussusceptum [B], distended loop of small

bowel [C] and ii) haemangioma of right quadratus lumborum muscle (dark arrow).
Image by Lee C, Debnath D, Whitburn T, Farrugia M, Gonzalez F CC BY 2.0 · Source

A 45-year-old male with a known history of Blue Rubber Bleb Naevus Syndrome, characterised by recurrent gastrointestinal bleeding and multiple cutaneous vascular lesions, presents to the emergency department with acute onset severe, colicky abdominal pain, nausea, and vomiting. On examination, his abdomen is distended and diffusely tender with reduced bowel sounds. Vital signs are within normal limits. An urgent abdominal CT scan is performed. Considering the patient's history, acute presentation, and the findings on the abdominal CT scan, what is the most appropriate immediate management strategy?

A. Urgent surgical consultation for operative management
B. Attempt non-operative reduction via hydrostatic or pneumatic enema
C. Perform urgent upper and lower endoscopy to identify bleeding lesions
D. Initiate conservative management with intravenous fluids and nasogastric tube insertion
E. Administer broad-spectrum antibiotics and observe closely
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A 24-year-old woman presents to the emergency department with a 3-day history of fever, sore throat, and fatigue. She also reports a rash that developed after taking amoxicillin prescribed by her GP for a presumed bacterial throat infection. On examination, she has cervical lymphadenopathy, a diffuse maculopapular rash, and mild splenomegaly. Her vital signs are stable. A monospot test is positive. Which of the following is the most likely explanation for the rash?

A. Scarlet fever
B. Allergic reaction to amoxicillin
C. Amoxicillin-induced rash in the context of infectious mononucleosis
D. Drug-induced lupus erythematosus
E. Stevens-Johnson syndrome
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A 78-year-old man with a history of chronic atrial fibrillation and hypertension presents to the emergency department with sudden onset of severe pain, numbness, and coldness in his left leg, starting approximately 3 hours ago. He is currently taking aspirin 100mg daily. On examination, his left foot and lower calf are pale and cool to touch. Pedal pulses are absent, popliteal pulse is weak. Sensation is decreased below the ankle, and motor function is preserved but weak. Capillary refill in the toes is delayed. His heart rate is irregularly irregular at 95 bpm, blood pressure 140/85 mmHg. What is the most appropriate initial management step?

A. Initiate intravenous unfractionated heparin and consult vascular surgery urgently.
B. Administer a bolus of intravenous fluid and analgesia.
C. Start a continuous infusion of alteplase.
D. Order an urgent CT angiography of the left lower limb.
E. Arrange for an urgent venous duplex ultrasound to rule out deep vein thrombosis.
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Ultrasonographic picture taken from a patient with left ureteral stone with hydronephrosis, created in Taiwan
Image by morning2k CC BY 2.5 · Source

A 38-year-old male presents to the emergency department complaining of sudden onset, severe left flank pain that radiates to his groin. He reports associated nausea and vomiting. He denies any fever, dysuria, or hematuria. His vital signs are: Temperature 37.0°C, Heart Rate 88 bpm, Blood Pressure 130/80 mmHg, Respiratory Rate 16 breaths/min, and SpO2 98% on room air. A urine dipstick is positive for blood. An ultrasound is performed, and the image is shown. Given the clinical presentation and the ultrasound findings, what is the MOST appropriate next step in management?

A. Administer intravenous ketorolac and discharge with outpatient urology follow-up
B. Consult nephrology for possible percutaneous nephrostomy
C. Order a non-contrast CT scan of the abdomen and pelvis
D. Insert a Foley catheter to monitor urine output
E. Start intravenous antibiotics for presumed pyelonephritis
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A 32-year-old man presents to the emergency department with severe abdominal pain that started suddenly 6 hours ago. The pain is located in the right lower quadrant and is associated with nausea and vomiting. On examination, he has rebound tenderness and guarding in the right lower quadrant. His temperature is 37.8°C, heart rate is 110 beats per minute, and blood pressure is 120/80 mmHg. A CT scan of the abdomen shows an inflamed appendix with surrounding fat stranding. What is the most appropriate next step in management?

A. Percutaneous drainage
B. Laparoscopic cholecystectomy
C. Appendectomy
D. Observation and repeat imaging
E. Intravenous antibiotics only
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A 60-year-old man presents to the emergency department with sudden onset of chest pain and shortness of breath. He has a history of chronic obstructive pulmonary disease (COPD) and is a current smoker. On examination, he is tachypneic and has decreased breath sounds on the right side. A chest X-ray reveals a large right-sided pneumothorax. What is the most appropriate initial management?

A. Start intravenous antibiotics
B. Insert a chest tube
C. Perform needle decompression
D. Administer high-flow oxygen
E. Order a CT scan of the chest
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A 62-year-old man with a history of chronic obstructive pulmonary disease (COPD) and type 2 diabetes presents to the emergency department with increasing shortness of breath over the past two days. He reports a productive cough with greenish sputum and denies chest pain. On examination, he is using accessory muscles to breathe, has a respiratory rate of 28 breaths per minute, and oxygen saturation of 88% on room air. His blood pressure is 130/85 mmHg, and his heart rate is 105 bpm. Auscultation of the chest reveals diffuse wheezing and decreased breath sounds bilaterally. An arterial blood gas analysis shows pH 7.32, PaCO2 55 mmHg, and PaO2 60 mmHg. What is the most appropriate next step in the management of this patient?

A. Initiate non-invasive positive pressure ventilation (NIPPV)
B. Provide supplemental oxygen via nasal cannula
C. Administer intravenous corticosteroids
D. Administer a bronchodilator nebulizer treatment
E. Start broad-spectrum antibiotics
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Ultrasonographic picture taken from a patient with left ureteral stone with hydronephrosis, created in Taiwan
Image by morning2k CC BY 2.5 · Source

A 45-year-old male presents to the ED with left flank pain that started suddenly 6 hours ago. He describes the pain as a sharp, cramping sensation radiating to his groin. He also reports nausea and one episode of vomiting. His vital signs are stable: BP 120/80 mmHg, HR 78 bpm, RR 16 breaths/min, Temp 37.1°C. Urine dipstick shows 2+ blood. A renal ultrasound is performed, and the image is shown. Assuming the patient's pain is not controlled with oral analgesics, what is the MOST appropriate next step?

A. Consult urology for emergent ureteroscopy
B. Start intravenous fluids at 250 mL/hr
C. Order a non-contrast CT scan of the abdomen and pelvis
D. Discharge home with tamsulosin and analgesics
E. Administer intravenous ketorolac
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An incarcerated inguinal hernia as seen on CT
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 72-year-old man presents with sudden onset of severe right groin pain and a firm, non-reducible bulge. He reports mild nausea but denies vomiting or change in bowel habit. Vital signs are stable. A CT scan of the pelvis is performed, as shown. Considering the clinical context and the imaging findings, what is the most appropriate immediate management?

A. Obtain a groin ultrasound for further assessment
B. Attempt manual reduction under sedation
C. Arrange for elective surgical consultation
D. Administer analgesia and observe closely
E. Emergency surgical exploration and repair
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A 35-year-old woman presents to the emergency department with a 3-day history of fever, chills, and a productive cough with greenish sputum. She has a history of asthma and is currently on inhaled corticosteroids. On examination, her temperature is 38.5°C, blood pressure is 120/80 mmHg, heart rate is 110 bpm, and respiratory rate is 24 breaths per minute. Auscultation of the chest reveals wheezing and crackles in the right lower lung field. A chest X-ray shows consolidation in the right lower lobe. What is the most appropriate initial antibiotic therapy for this patient, considering her asthma and current presentation?

A. Azithromycin
B. Amoxicillin-clavulanate
C. Ciprofloxacin
D. Levofloxacin
E. Doxycycline
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A 43-year-old is unconscious with low blood glucose (1.8 mmol/L), has a history of insulin use and alcohol intake. What is the next step?

A. 16G IV + 10% glucose, 150-200 ml over 15 minutes.
B. Give oral glucose.
C. Give 1 mg of glucagon intramuscularly.
D. Give IV 50% glucose.
E. Give subcutaneous insulin.
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An incarcerated inguinal hernia as seen on CT
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 78-year-old man presents to the emergency department with acute, severe right groin pain and a palpable, non-reducible mass. He reports associated nausea but denies vomiting or changes in bowel habit. His vital signs are within normal limits, and bowel sounds are audible. A CT scan of the pelvis is performed, the findings of which are depicted in the image. Given the clinical context and the information revealed by the imaging study, what is the most appropriate immediate management strategy?

A. Urgent surgical consultation for operative intervention.
B. Attempt manual reduction under adequate analgesia and sedation.
C. Request an urgent Doppler ultrasound to assess blood flow to the contents.
D. Initiate intravenous broad-spectrum antibiotics and monitor closely.
E. Arrange for elective hernia repair in the coming weeks.
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Ultrasonographic picture taken from a patient with left ureteral stone with hydronephrosis, created in Taiwan
Image by morning2k CC BY 2.5 · Source

A 38-year-old male presents to the emergency department complaining of sudden onset, severe left flank pain that radiates to his groin. He reports associated nausea and vomiting. He denies any fever, dysuria, or hematuria. His vital signs are stable: blood pressure 120/80 mmHg, heart rate 88 bpm, respiratory rate 16 breaths/min, and temperature 37.0°C. A urinalysis reveals microscopic hematuria. A point-of-care ultrasound is performed, and the image is shown. Given the clinical presentation and ultrasound findings, what is the MOST appropriate next step in management?

A. Consult nephrology for possible percutaneous nephrostomy
B. Insert a Foley catheter to monitor urine output
C. Prescribe oral antibiotics for presumed pyelonephritis
D. Order a non-contrast CT scan of the abdomen and pelvis
E. Administer intravenous ketorolac and discharge with outpatient urology follow-up
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An incarcerated inguinal hernia as seen on CT
Image by James Heilman, MD CC BY-SA 3.0 · Source

An 80-year-old male presents to the emergency department with sudden onset of severe right groin pain and a non-reducible bulge. He has a history of a reducible inguinal hernia. Vitals are stable. A CT scan of the pelvis is performed. Considering the clinical presentation and the provided imaging, what is the most appropriate immediate management step?

A. Discharge home with advice to see GP if symptoms worsen.
B. Urgent surgical consultation for potential operative intervention.
C. Administer analgesia and observe for spontaneous reduction.
D. Attempt manual reduction under sedation.
E. Order an urgent ultrasound of the groin.
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Giant hiatal hernia, CT image. 63 year old man.
Image by Jmarchn CC BY 4.0 · Source

A 63-year-old man presents to the ED with increasing shortness of breath and epigastric discomfort, particularly after meals. He has a history of well-controlled hypertension and takes no regular medications. Physical examination reveals decreased breath sounds at the left lung base. An abdominal CT scan is performed, the axial view is shown. What is the MOST appropriate next step in management?

A. Discharge with reassurance and follow-up with a gastroenterologist in 6 months
B. Barium swallow study to further evaluate the anatomy
C. Surgical consultation for elective repair
D. Initiate a trial of proton pump inhibitors and lifestyle modifications
E. Esophageal manometry to assess esophageal motility
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Ultrasonographic picture taken from a patient with left ureteral stone with hydronephrosis, created in Taiwan
Image by morning2k CC BY 2.5 · Source

A 45-year-old male presents to the ED with left flank pain radiating to his groin. He reports nausea but no vomiting. Vitals are stable. A focused ultrasound is performed, as shown. What is the MOST appropriate next step in management?

A. Non-contrast CT of the abdomen and pelvis
B. Perform intravenous pyelogram
C. Insert a Foley catheter
D. Administer intravenous antibiotics
E. Discharge with analgesics and follow-up with urology
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Upright X-ray demonstrating small bowel obstruction
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents with abdominal pain, distension, and obstipation for 3 days, with a history of multiple abdominal surgeries. Vitals are HR 110, BP 110/70, T 37.8. Exam shows a distended abdomen with high-pitched bowel sounds. An upright abdominal X-ray is shown. Considering the clinical context and the imaging findings, which of the following is the MOST likely expected outcome with initial non-operative management?

A. Requirement for immediate surgical intervention
B. Resolution of symptoms within 48-72 hours
C. Spontaneous resolution within minutes of presentation
D. Need for long-term parenteral nutrition
E. Development of large bowel obstruction
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A 34-year-old man presents to the Emergency Department with acute-onset shortness of breath. A CT pulmonary angiogram (CTPA) is ordered, shown in the photograph, confirming a diagnosis of pulmonary embolism. Which of the following is the most appropriate initial treatment option for this patient?

A. Thrombolytic therapy.
B. Caval filter.
C. Unfractionated heparin or low-molecular weight heparin (LMWH).
D. Dabigatran.
E. Warfarin.
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A 45-year-old woman presents to the emergency department with acute onset of severe right upper quadrant abdominal pain radiating to the back, accompanied by nausea and vomiting. She has a history of gallstones but no previous surgeries. On examination, she is febrile with a temperature of 38.5°C, her heart rate is 110 bpm, and she has tenderness in the right upper quadrant with a positive Murphy's sign. Laboratory tests reveal elevated white blood cell count, elevated liver enzymes, and elevated serum amylase. An abdominal ultrasound shows gallstones and a thickened gallbladder wall. Which of the following is the most appropriate next step in management?

A. Intravenous antibiotics and cholecystectomy
B. Magnetic resonance cholangiopancreatography (MRCP)
C. Endoscopic retrograde cholangiopancreatography (ERCP)
D. Observation and pain management
E. Percutaneous cholecystostomy
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A 35-year-old man presents to the emergency department with severe right-sided flank pain that started suddenly and radiates to the groin. He describes the pain as sharp and colicky. He has had similar episodes in the past but never this severe. He denies fever, dysuria, or hematuria. On examination, he is in obvious distress, with a blood pressure of 140/90 mmHg, heart rate of 110 bpm, and respiratory rate of 22 breaths per minute. Abdominal examination reveals tenderness in the right flank but no guarding or rebound tenderness. Urinalysis shows microscopic hematuria. Which of the following is the most appropriate initial imaging study to confirm the diagnosis?

A. X-ray of the abdomen
B. Intravenous pyelogram (IVP)
C. Abdominal ultrasound
D. MRI of the abdomen
E. Non-contrast CT scan of the abdomen and pelvis
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Upright X-ray demonstrating small bowel obstruction
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male with a history of multiple abdominal surgeries presents to the emergency department complaining of abdominal pain, distension, and obstipation for the past 3 days. His vital signs are: HR 110 bpm, BP 110/70 mmHg, RR 22 breaths/min, SpO2 97% on room air, and temperature 37.8°C. Physical examination reveals a distended abdomen with high-pitched bowel sounds. An upright abdominal X-ray is performed, as shown. Given the clinical context and the radiographic findings, which demonstrate significant intraluminal gas accumulation proximal to the likely site of obstruction, what is the predominant source of this gas?

A. Diffusion from blood
B. Swallowed atmospheric air
C. Pancreatic enzyme activity
D. Biliary secretion
E. Bacterial fermentation
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Upright X-ray demonstrating small bowel obstruction
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 75-year-old female presents to the emergency department with a 24-hour history of worsening colicky abdominal pain, nausea, and multiple episodes of bilious vomiting. She reports no passage of flatus or stool for the past 18 hours. Her past medical history includes an open appendectomy 30 years ago and a hysterectomy 10 years ago. On examination, she is afebrile, heart rate 92 bpm, blood pressure 130/80 mmHg, respiratory rate 18/min, oxygen saturation 98% on room air. Her abdomen is distended and diffusely tender to palpation, with high-pitched tinkling bowel sounds on auscultation. A plain abdominal X-ray series, including the image provided, was obtained. Given the clinical presentation and the findings demonstrated in the provided image, which of the following is the most appropriate *next* investigation to guide definitive management?

A. Repeat plain abdominal X-ray series in 6 hours
B. Upper endoscopy
C. Barium enema
D. MRI of the abdomen
E. CT scan of the abdomen and pelvis with intravenous contrast
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Upright X-ray demonstrating small bowel obstruction
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 72-year-old male presents with abdominal distension, vomiting, and inability to pass flatus for 48 hours. He has a history of prior bowel resection. Examination reveals a tympanitic abdomen and tenderness to palpation. His vitals are stable. An abdominal X-ray is performed, as shown. Considering the clinical context and the radiographic findings, what is the primary purpose of inserting a nasogastric tube in this patient?

A. Obtaining a sample of gastric contents for analysis.
B. Administering oral contrast for further imaging.
C. Decompressing the dilated bowel loops and reducing vomiting.
D. Providing nutritional support to the patient.
E. Facilitating the passage of flatus.
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PET-CT of a tuberculoma
Image by Annemie Snoeckx, Pieter Reyntiens, Damien Desbuquoit, Maarten J. Spinhoven, Paul E. Van Schil, Jan P. van Meerbeeck, Paul M. Parizel CC BY 4.0 · Source

A 32-year-old male, originally from a high-TB prevalence country, presents to the emergency department with a persistent cough for the past 3 weeks, night sweats, and a 5 kg weight loss. He denies any fever or shortness of breath. Physical examination reveals normal breath sounds bilaterally, with no wheezes or crackles. His vital signs are stable: temperature 37.2°C, heart rate 88 bpm, blood pressure 120/80 mmHg, and oxygen saturation 98% on room air. A chest X-ray was initially interpreted as showing a possible lung mass, prompting further investigation with a PET-CT scan, the axial view of which is shown. Sputum samples have been sent for microscopy and culture, but results are pending. Given the clinical presentation and the imaging findings, what is the MOST appropriate next step in management?

A. Order a bronchoscopy with bronchoalveolar lavage and transbronchial biopsy
B. Schedule a follow-up PET-CT scan in 3 months to monitor for changes in size and metabolic activity
C. Prescribe a course of broad-spectrum antibiotics to cover community-acquired pneumonia
D. Perform a CT-guided needle biopsy of the lesion for definitive diagnosis
E. Initiate a multi-drug anti-tuberculosis therapy regimen
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A 45-year-old man presents to the emergency department with severe epigastric pain radiating to his back, which started suddenly a few hours ago. He has a history of alcohol use disorder and has been drinking heavily over the past week. On examination, he is diaphoretic and in distress. His vital signs show a blood pressure of 100/60 mmHg, heart rate of 110 bpm, respiratory rate of 22 breaths per minute, and temperature of 37.8°C. Laboratory tests reveal elevated serum lipase and amylase levels. An abdominal ultrasound shows no gallstones. Which of the following is the most appropriate initial management step for this patient?

A. Nasogastric tube insertion
B. Intravenous fluid resuscitation
C. Initiation of broad-spectrum antibiotics
D. Immediate surgical consultation
E. Oral rehydration therapy
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A 28-year-old woman presents to the emergency department with sudden onset of severe right lower abdominal pain. She reports nausea and vomiting but denies fever or urinary symptoms. Her last menstrual period was two weeks ago, and she is sexually active. On examination, she has tenderness in the right lower quadrant with guarding. A pelvic ultrasound reveals a 5 cm right ovarian cyst with free fluid in the pelvis. What is the most likely diagnosis?

A. Pelvic inflammatory disease
B. Ruptured ovarian cyst
C. Ovarian torsion
D. Ectopic pregnancy
E. Appendicitis
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A 55-year-old man presents to the emergency department with sudden onset severe abdominal pain radiating to the back. He has a history of hypertension and is a smoker. On examination, he is diaphoretic and in distress, with a blood pressure of 90/60 mmHg and a heart rate of 110 bpm. Abdominal examination reveals a pulsatile mass in the midline. What is the most likely diagnosis?

A. Acute myocardial infarction
B. Acute pancreatitis
C. Perforated peptic ulcer
D. Renal colic
E. Ruptured abdominal aortic aneurysm
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A 28-year-old woman presents to the emergency department with severe lower abdominal pain and vaginal bleeding. She is 8 weeks pregnant by last menstrual period. She reports no fever or chills. On examination, her blood pressure is 100/60 mmHg, heart rate is 110 bpm, and she appears pale and diaphoretic. Abdominal examination reveals tenderness in the lower quadrants without rebound tenderness or guarding. A pelvic examination shows a closed cervical os with moderate bleeding. A bedside transvaginal ultrasound reveals an empty uterus. Which of the following is the most appropriate next step in management?

A. Administer methotrexate
B. Perform an exploratory laparotomy
C. Administer anti-D immunoglobulin
D. Observe and repeat ultrasound in 48 hours
E. Perform a dilation and curettage
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A 32-year-old woman presents to the emergency department with a 2-day history of fever, headache, and a rash that started on her wrists and ankles and has now spread to her trunk. She recently returned from a camping trip in the Northern Territory. On examination, she is febrile at 38.5°C, with a heart rate of 110 bpm and blood pressure of 100/70 mmHg. The rash is maculopapular and blanching. Laboratory tests reveal thrombocytopenia and elevated liver enzymes. Which of the following is the most likely diagnosis?

A. Systemic lupus erythematosus
B. Drug reaction
C. Rickettsial infection
D. Viral exanthem
E. Meningococcal infection
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 68-year-old male presents to the ED with left lower quadrant abdominal pain, fever, and leukocytosis. A CT scan of the abdomen and pelvis is performed. Based on the imaging, what is the MOST appropriate next step in management?

A. IV antibiotics and bowel rest
B. Surgical resection of the affected bowel segment
C. Flexible sigmoidoscopy to rule out malignancy
D. Increase dietary fiber intake and follow up with GP
E. Stool culture to rule out infectious colitis
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A 32-year-old woman presents to the emergency department with severe right lower quadrant abdominal pain, nausea, and vomiting. She reports her last menstrual period was 6 weeks ago. On examination, she has tenderness and guarding in the right lower quadrant. A urine pregnancy test is positive. What is the most appropriate next step in management?

A. Prescribe analgesics and discharge
B. Schedule an exploratory laparotomy
C. Perform a transvaginal ultrasound
D. Administer methotrexate
E. Order a CT scan of the abdomen
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An incarcerated inguinal hernia as seen on CT
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents to the emergency department with a 12-hour history of severe, constant left groin pain. He reports a bulge in his groin that has been present for several years, which he can usually reduce himself. However, today he has been unable to push it back in, and the pain has become excruciating. He denies any fever, nausea, or vomiting. On examination, his vital signs are stable: temperature 37.0°C, heart rate 88 bpm, blood pressure 130/80 mmHg, respiratory rate 16 breaths/min, and oxygen saturation 98% on room air. Abdominal examination is unremarkable. Palpation of the left groin reveals a firm, tender mass that is non-reducible. The overlying skin is erythematous, but there is no crepitus. A CT scan of the abdomen and pelvis is performed, and an axial slice is shown. Considering the clinical presentation and the findings demonstrated in the image, what is the MOST appropriate next step in management?

A. Attempt manual reduction of the mass under conscious sedation
B. Order an urgent ultrasound of the groin to assess for vascular compromise
C. Administer intravenous fluids and analgesia, then observe for signs of spontaneous reduction over 24 hours
D. Urgent surgical consultation for operative management
E. Prescribe oral antibiotics and arrange for outpatient surgical review within one week
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Giant hiatal hernia, CT image. 63 year old man.
Image by Jmarchn CC BY 4.0 · Source

A 63-year-old man presents to the emergency department complaining of increasing shortness of breath and epigastric discomfort over the past several months. He reports feeling full quickly after eating only small amounts. He denies any chest pain, fever, or recent weight loss. His past medical history includes hypertension and well-controlled type 2 diabetes. He takes lisinopril and metformin daily. On examination, his vital signs are stable: blood pressure 130/80 mmHg, heart rate 82 bpm, respiratory rate 18 breaths/min, and oxygen saturation 96% on room air. Auscultation of the chest reveals decreased breath sounds at the left base. Abdominal examination reveals mild epigastric tenderness to palpation, but no rebound tenderness or guarding. The provided image was obtained. Which of the following is the MOST appropriate next step in management?

A. Initiate a proton pump inhibitor and monitor symptoms
B. Esophageal manometry
C. Endoscopic surveillance every 3 years
D. Surgical repair
E. Barium swallow study
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Adult with suspected aspiration pneumonia. Initial antibiotic?

A. Doxycycline
B. Amoxicillin-clavulanate
C. Ciprofloxacin
D. Ceftriaxone
E. Azithromycin
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CT scan showing hemothorax caused by warfarin use
Image by Cevik Y CC BY 3.0 · Source

A 75-year-old male on warfarin for atrial fibrillation presents with acute dyspnoea and pleuritic chest pain. He is hypotensive with a BP of 90/60 mmHg and tachycardic at 110 bpm. His INR is 7.2. A chest CT is performed (image attached). Considering the clinical context and imaging findings, what is the MOST appropriate immediate management step?

A. Administer intravenous Vitamin K and Prothrombinex-VF
B. Initiate high-flow nasal cannula oxygen
C. Arrange for urgent surgical consultation for thoracotomy
D. Perform urgent tube thoracostomy
E. Administer intravenous furosemide
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A 62-year-old woman presents to the emergency department with acute onset of chest pain and shortness of breath. She describes the pain as sharp and worse with inspiration. She has a history of deep vein thrombosis and is currently on warfarin. On examination, her blood pressure is 110/70 mmHg, heart rate is 110 bpm, respiratory rate is 24 breaths per minute, and oxygen saturation is 88% on room air. Her jugular venous pressure is elevated, and she has clear lung fields on auscultation. An ECG shows sinus tachycardia with right axis deviation. Which of the following is the most likely diagnosis?

A. Acute myocardial infarction
B. Pulmonary embolism
C. Pericarditis
D. Pneumothorax
E. Aortic dissection
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